Matehuala to San Luis Potosí bus with Senda
Senda buses from Matehuala Bus Terminal to San Luis Potosí Bus Station (Terminal Terrestre Potosina): around 2h 20min, 12 departures on a typical weekday and fares from MX$293.
Why travel with Senda from Matehuala to San Luis Potosí
Grupo Senda has run buses in northern Mexico since 1934. On the Matehuala to San Luis Potosí route you get:
Adjustable seats
Wi-Fi on board
Power sockets
Restroom on board
Air conditioning
Luggage included
Onboard entertainment
Seat belts and monitored buses
Digital ticket
Digital ticket
Directly to your email
Secure payment
Pay online in MXN or your currency
Book in your language
English, Spanish and more
Book your Matehuala to San Luis Potosí bus
Compare every Senda departure for your date, choose your seat and pay online. Your e-ticket arrives by email. The answers to the most common questions are below.
Matehuala to San Luis Potosí by bus at a glance
12 departures on a typical weekday
First bus 12:30 AM, last bus 9:40 PM
From Matehuala Bus Terminal
To San Luis Potosí Bus Station (Terminal Terrestre Potosina)
Around 2h 20min travel time
About 190 km, fares from MX$293
Matehuala to San Luis Potosí by bus: schedule, stations and trip
On Wednesday, November 25, 2026, the booking flow showed 12 Senda departures from Matehuala Bus Terminal to San Luis Potosí Bus Station (Terminal Terrestre Potosina) (13 on Saturday, November 28, 2026). Departure times that day: 12:30 AM, 2:40 AM, 4:20 AM, 4:35 AM, 5:40 AM, 9:55 AM, 12:35 PM, 2:35 PM, 4:40 PM, 5:40 PM, 7:10 PM, 9:40 PM.
Schedules change by date and season, so search your travel date to see the exact times and fares.
Where the bus leaves from
Matehuala Bus Terminal, Av. Héroes Potosinos 2101, Matehuala, San Luis Potosí. The terminal is on the south side of Matehuala, a few minutes by taxi from the town center. Local buses and taxis continue to Real de Catorce.
Where the bus arrives
San Luis Potosí Bus Station (Terminal Terrestre Potosina), Carretera México km 2.5 / Blvd. San Luis, San Luis Potosí. The Terminal Terrestre Potosina (TTP) is on the east side of the city; a taxi or ride-hailing app takes about 15 minutes to the historic center.
The trip
The trip covers about 190 km, mostly on highway 57. Senda buses take around 2 hours 20 minutes (between 2h 10min and 2h 45min depending on the departure). Traffic, roadworks and checkpoints can add time.
Visiting Real de Catorce
Coming from Real de Catorce? Local buses and taxis bring you back to Matehuala, where Senda buses leave for San Luis Potosí throughout the day.
Station guides
Address, access and every Senda departure: Matehuala Bus Terminal · San Luis Potosí Bus Station (Terminal Terrestre Potosina).
Arriving in San Luis Potosí
San Luis Potosí is a colonial state capital with a UNESCO-listed stretch of the Camino Real de Tierra Adentro, the Plaza de Armas and cathedral, the Teatro de la Paz and lively pedestrian streets. It is also the gateway to Real de Catorce in the Altiplano and to the waterfalls and rivers of the Huasteca Potosina.