Monterrey to San Luis Potosí bus with Senda
Senda buses from Monterrey Central Bus Station to San Luis Potosí Bus Station (Terminal Terrestre Potosina): around 7h, 12 departures on a typical weekday and fares from MX$764.
Why travel with Senda from Monterrey to San Luis Potosí
Grupo Senda has run buses in northern Mexico since 1934. On the Monterrey to San Luis Potosí route you get:
Adjustable seats
Wi-Fi on board
Power sockets
Restroom on board
Air conditioning
Luggage included
Onboard entertainment
Seat belts and monitored buses
Digital ticket
Digital ticket
Directly to your email
Secure payment
Pay online in MXN or your currency
Book in your language
English, Spanish and more
Book your Monterrey to San Luis Potosí bus
Compare every Senda departure for your date, choose your seat and pay online. Your e-ticket arrives by email. The answers to the most common questions are below.
Monterrey to San Luis Potosí by bus at a glance
12 departures on a typical weekday
First bus 1:00 AM, last bus 11:59 PM
From Monterrey Central Bus Station
To San Luis Potosí Bus Station (Terminal Terrestre Potosina)
Around 7h travel time
About 515 km, fares from MX$764
Monterrey to San Luis Potosí by bus: schedule, stations and trip
On Wednesday, November 25, 2026, the booking flow showed 12 Senda departures from Monterrey Central Bus Station to San Luis Potosí Bus Station (Terminal Terrestre Potosina) (13 on Saturday, November 28, 2026). Departure times that day: 1:00 AM, 8:00 AM, 10:00 AM, 12:00 PM, 1:00 PM, 2:30 PM, 4:35 PM, 7:05 PM, 9:00 PM, 10:00 PM, 11:00 PM, 11:59 PM.
Schedules change by date and season, so search your travel date to see the exact times and fares.
Where the bus leaves from
Monterrey Central Bus Station, Av. Cristóbal Colón 855, Colonia Industrial, Monterrey, Nuevo León. The Central de Autobuses is next to Central station on Metrorrey Line 1, a few minutes from downtown Monterrey by metro, taxi or ride-hailing app.
Where the bus arrives
San Luis Potosí Bus Station (Terminal Terrestre Potosina), Carretera México km 2.5 / Blvd. San Luis, San Luis Potosí. The Terminal Terrestre Potosina (TTP) is on the east side of the city; a taxi or ride-hailing app takes about 15 minutes to the historic center.
The trip
The trip covers about 515 km, mostly on highway 57 via Saltillo and Matehuala. Senda buses take around 7 hours (between 6h 50min and 7h 25min depending on the departure). Traffic, roadworks and checkpoints can add time. With 5 departures in the evening or at night, you can travel overnight and arrive in the morning.
Station guides
Address, access and every Senda departure: Monterrey Central Bus Station · San Luis Potosí Bus Station (Terminal Terrestre Potosina).
Arriving in San Luis Potosí
San Luis Potosí is a colonial state capital with a UNESCO-listed stretch of the Camino Real de Tierra Adentro, the Plaza de Armas and cathedral, the Teatro de la Paz and lively pedestrian streets. It is also the gateway to Real de Catorce in the Altiplano and to the waterfalls and rivers of the Huasteca Potosina.