Saltillo to Mexico City bus with Senda
Senda buses from Saltillo Central Bus Station to Mexico City Northern Bus Station: around 12h 35min, 3 departures on a typical weekday and fares from MX$880.
Why travel with Senda from Saltillo to Mexico City
Grupo Senda has run buses in northern Mexico since 1934. On the Saltillo to Mexico City route you get:
Adjustable seats
Wi-Fi on board
Power sockets
Restroom on board
Air conditioning
Luggage included
Onboard entertainment
Seat belts and monitored buses
Digital ticket
Digital ticket
Directly to your email
Secure payment
Pay online in MXN or your currency
Book in your language
English, Spanish and more
Book your Saltillo to Mexico City bus
Compare every Senda departure for your date, choose your seat and pay online. Your e-ticket arrives by email. The answers to the most common questions are below.
Saltillo to Mexico City by bus at a glance
3 departures on a typical weekday
First bus 12:50 AM, last bus 8:25 PM
From Saltillo Central Bus Station
To Mexico City Northern Bus Station
Around 12h 35min travel time
About 840 km, fares from MX$880
Saltillo to Mexico City by bus: schedule, stations and trip
On Wednesday, November 25, 2026, the booking flow showed 3 Senda departures from Saltillo Central Bus Station to Mexico City Northern Bus Station. Departure times that day: 12:50 AM, 6:25 AM, 8:25 PM.
Schedules change by date and season, so search your travel date to see the exact times and fares.
Where the bus leaves from
Saltillo Central Bus Station, Terminal Central de Autobuses, Colonia Lourdes, Saltillo, Coahuila. Saltillo Central Bus Station is south-west of the historic center; taxis and ride-hailing apps connect it with the city center and the industrial parks.
Where the bus arrives
Mexico City Northern Bus Station, Eje Central Lázaro Cárdenas 4907, Gustavo A. Madero, Mexico City. The Northern Bus Station (Central del Norte) is next to Autobuses del Norte station on Metro Line 5. Authorized taxis can be booked at the official taxi booths inside the terminal.
The trip
The trip covers about 840 km, mostly on highway 57 via San Luis Potosí and Querétaro. Senda buses take around 12 hours 35 minutes (between 12h 30min and 12h 50min depending on the departure). Traffic, roadworks and checkpoints can add time.
Also from Saltillo Indio station
Senda runs 3 more buses a day to Mexico City from its Saltillo Indio station (Periférico Luis Echeverría 1550, north Saltillo), at 12:10 AM, 6:00 AM, 8:05 PM. Search the city of Saltillo to compare both stations.
Station guides
Address, access and every Senda departure: Saltillo Central Bus Station.
Arriving in Mexico City
Mexico City is the capital and the largest city in Mexico, with the Zócalo and historic center, the Palacio de Bellas Artes, Chapultepec Park and the National Museum of Anthropology, Coyoacán and Roma–Condesa. The Northern Bus Station connects with Metro Line 5, so it is easy to continue your trip across the city.