San Luis Potosí to Mexico City bus with Senda
Senda buses from San Luis Potosí Bus Station (Terminal Terrestre Potosina) to Mexico City Northern Bus Station: around 6h, 7 departures on a typical weekday and fares from MX$587.
Why travel with Senda from San Luis Potosí to Mexico City
Grupo Senda has run buses in northern Mexico since 1934. On the San Luis Potosí to Mexico City route you get:
Adjustable seats
Wi-Fi on board
Power sockets
Restroom on board
Air conditioning
Luggage included
Onboard entertainment
Seat belts and monitored buses
Digital ticket
Digital ticket
Directly to your email
Secure payment
Pay online in MXN or your currency
Book in your language
English, Spanish and more
Book your San Luis Potosí to Mexico City bus
Compare every Senda departure for your date, choose your seat and pay online. Your e-ticket arrives by email. The answers to the most common questions are below.
San Luis Potosí to Mexico City by bus at a glance
7 departures on a typical weekday
First bus 2:05 AM, last bus 11:59 PM
From San Luis Potosí Bus Station (Terminal Terrestre Potosina)
To Mexico City Northern Bus Station
Around 6h travel time
About 415 km, fares from MX$587
San Luis Potosí to Mexico City by bus: schedule, stations and trip
On Wednesday, November 25, 2026, the booking flow showed 7 Senda departures from San Luis Potosí Bus Station (Terminal Terrestre Potosina) to Mexico City Northern Bus Station (8 on Saturday, November 28, 2026). Departure times that day: 2:05 AM, 2:45 AM, 4:25 AM, 6:20 AM, 7:00 AM, 12:35 PM, 11:59 PM.
Schedules change by date and season, so search your travel date to see the exact times and fares.
Where the bus leaves from
San Luis Potosí Bus Station (Terminal Terrestre Potosina), Carretera México km 2.5 / Blvd. San Luis, San Luis Potosí. The Terminal Terrestre Potosina (TTP) is on the east side of the city; a taxi or ride-hailing app takes about 15 minutes to the historic center.
Where the bus arrives
Mexico City Northern Bus Station, Eje Central Lázaro Cárdenas 4907, Gustavo A. Madero, Mexico City. The Northern Bus Station (Central del Norte) is next to Autobuses del Norte station on Metro Line 5. Authorized taxis can be booked at the official taxi booths inside the terminal.
The trip
The trip covers about 415 km, mostly on highway 57 via Querétaro. Senda buses take around 6 hours (between 5h 55min and 6h 40min depending on the departure). Traffic, roadworks and checkpoints can add time. With 4 departures in the evening or at night, you can travel overnight and arrive in the morning.
Station guides
Address, access and every Senda departure: San Luis Potosí Bus Station (Terminal Terrestre Potosina).
Arriving in Mexico City
Mexico City is the capital and the largest city in Mexico, with the Zócalo and historic center, the Palacio de Bellas Artes, Chapultepec Park and the National Museum of Anthropology, Coyoacán and Roma–Condesa. The Northern Bus Station connects with Metro Line 5, so it is easy to continue your trip across the city.